However, according to the paper, the independent data monitoring committee has confirmed that none of these were considered related to the vaccine.ĭespite these data, there is still a significant controversy surrounding the vaccine. These side effects are similar to those of the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, as noted by the Centers for Disease Control and Prevention (CDC).Īuthors of the paper state that 45 out of 16,427 participants who received the vaccine reported serious adverse events, including deep vein thrombosis, hemorrhagic stroke, and hypertension. Based on the data, the most common side effects were:
#Vaccine after effects covid trial#
The Johnson & Johnson COVID-19 vaccine, also an adenovirus-based vaccine, uses Ad26 for its single dose.Īn interim analysis of phase 3 clinical trial data, published in The Lancet in February 2021, reports on the efficacy and safety of the vaccine. The purpose of using two different types is to lower the possibility of the body developing antibodies against the adenovirus after the first dose, which could make the second dose ineffective. This then triggers the production of antibodies against this spike protein, preparing the immune system for a potential infection.Įach of the two doses uses a different type of adenovirus: first dose with type-26 (Ad26), then a booster dose with type-5 (Ad5).
They serve as the delivery vehicle for the DNA instructions to produce the spike protein of the SARS-CoV-2 virus in the body. Sputnik V is a two-part adenovirus viral vector vaccine with an efficacy rate of 91.6%.Īdenoviruses are a type of virus associated with the common cold and other illnesses. The vaccine is currently being reviewed in the European Union by the European Medicines Agency.
These countries include Argentina, Iran, and India. It is the first COVID-19 vaccine in the world to be authorized for use against the SARS-CoV-2 virus.Īlong with Russia, 64 countries have approved the vaccine. The Gamaleya National Center of Epidemiology and Microbiology in Moscow, Russia, developed a COVID-19 vaccine called Gam-COVID-Vac, more commonly known as Sputnik V.
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